{
  "object_id": "revive:losartan",
  "object_type": "Medication Decision Object",
  "schema_version": "1.0",
  "language": "en",
  "canonical_url": "/losartan/",
  "canonical_page_h1": "Losartan: Uses, Safety, Brands & Decision Guide",
  "entity_slug": "losartan",
  "primary_entity": "losartan",
  "entity_family": "ARBs",
  "page_kind": "drug_or_general",
  "decision_stage": "BOFU / decision",
  "ymyl": true,
  "source_phase": "Phase 2 Answer-First Citation Blocks",
  "decision_dimensions": [
    "role",
    "effectiveness",
    "dose",
    "side_effects",
    "interactions",
    "monitoring",
    "alternative",
    "switching",
    "comparison",
    "cost",
    "brand_generic",
    "comorbidity",
    "adherence",
    "risk_benefit",
    "failure",
    "patient_context",
    "natural_language",
    "decision_path",
    "summary"
  ],
  "answers": [
    {
      "query_id": "RZQ-01441",
      "question": "What is losartan mainly used for, and what decisions matter most when it is prescribed?",
      "short_answer": "past clinical response pattern matters in Losartan because a medicine that worked well but caused a specific problem creates a different decision from one that never achieved the therapeutic objective. For Losartan, documenting what improved, what did not improve, when medication-related problems appeared and whether doses were missed gives the next review something concrete to use. If Losartan is being researched after treatment failure, the useful question is whether the failure reflects dose, adherence, timing, interaction, wrong indication, intolerance or another clinical factor.",
      "citations": [
        {
          "label": "MedlinePlus drug information: Losartan",
          "url": "https://medlineplus.gov/druginfo/meds/a695008.html"
        },
        {
          "label": "DailyMed current human drug-label search: Losartan",
          "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=human&query=losartan"
        },
        {
          "label": "NHS medicine information: Losartan",
          "url": "https://www.nhs.uk/medicines/losartan/"
        }
      ]
    },
    {
      "query_id": "RZQ-01442",
      "question": "Where does losartan fit among other options in its drug class?",
      "short_answer": "A responsible Losartan side-by-side review explains where two choices differ and where they cannot be compared directly, instead of merely forcing every page to declare a winner. If Losartan involves two drugs, the opening question is whether they are substitutes, complementary treatments or options used in different clinical situations. If Losartan involves one product, compare that exact product with neighboring doses, generic versions or alternatives only after confirming the therapeutic aim.",
      "citations": [
        {
          "label": "MedlinePlus drug information: Losartan",
          "url": "https://medlineplus.gov/druginfo/meds/a695008.html"
        },
        {
          "label": "DailyMed current human drug-label search: Losartan",
          "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=human&query=losartan"
        },
        {
          "label": "NHS medicine information: Losartan",
          "url": "https://www.nhs.uk/medicines/losartan/"
        }
      ]
    }
  ],
  "related_questions": [
    {
      "query_id": "RZQ-01441",
      "question": "What is losartan mainly used for, and what decisions matter most when it is prescribed?",
      "priority": "P1",
      "micro_intent": "role"
    },
    {
      "query_id": "RZQ-01442",
      "question": "Where does losartan fit among other options in its drug class?",
      "priority": "P1",
      "micro_intent": "role"
    },
    {
      "query_id": "RZQ-01443",
      "question": "How should someone judge whether losartan is working?",
      "priority": "P2",
      "micro_intent": "effectiveness"
    },
    {
      "query_id": "RZQ-01444",
      "question": "What dose-related questions matter most with losartan?",
      "priority": "P2",
      "micro_intent": "dose"
    },
    {
      "query_id": "RZQ-01445",
      "question": "Which side effects are most likely to change the treatment decision around losartan?",
      "priority": "P2",
      "micro_intent": "side_effects"
    },
    {
      "query_id": "RZQ-01446",
      "question": "Which interaction questions matter most before using losartan?",
      "priority": "P2",
      "micro_intent": "interactions"
    },
    {
      "query_id": "RZQ-01447",
      "question": "What monitoring or follow-up can matter with losartan?",
      "priority": "P2",
      "micro_intent": "monitoring"
    },
    {
      "query_id": "RZQ-01448",
      "question": "When might someone need to discuss an alternative to losartan?",
      "priority": "P2",
      "micro_intent": "alternative"
    },
    {
      "query_id": "RZQ-01449",
      "question": "What should be reviewed before switching to or away from losartan?",
      "priority": "P2",
      "micro_intent": "switching"
    },
    {
      "query_id": "RZQ-01450",
      "question": "Which other medications are most useful to compare with losartan?",
      "priority": "P2",
      "micro_intent": "comparison"
    },
    {
      "query_id": "RZQ-01451",
      "question": "What determines the real-world cost and access of losartan?",
      "priority": "P2",
      "micro_intent": "cost"
    },
    {
      "query_id": "RZQ-01452",
      "question": "Does brand versus generic matter for losartan?",
      "priority": "P2",
      "micro_intent": "brand_generic"
    },
    {
      "query_id": "RZQ-01453",
      "question": "How can heart, kidney, blood-pressure, or vascular conditions affect the decision around losartan?",
      "priority": "P2",
      "micro_intent": "comorbidity"
    },
    {
      "query_id": "RZQ-01454",
      "question": "What practical issues can make losartan hard to use consistently?",
      "priority": "P2",
      "micro_intent": "adherence"
    },
    {
      "query_id": "RZQ-01455",
      "question": "How should someone balance the benefits and tolerability of losartan?",
      "priority": "P2",
      "micro_intent": "risk_benefit"
    },
    {
      "query_id": "RZQ-01456",
      "question": "What should be reviewed if losartan seems not to work?",
      "priority": "P2",
      "micro_intent": "failure"
    },
    {
      "query_id": "RZQ-01457",
      "question": "What if losartan works but causes an unwanted effect?",
      "priority": "P2",
      "micro_intent": "patient_context"
    },
    {
      "query_id": "RZQ-01458",
      "question": "What if losartan is tolerated but does not achieve the treatment goal?",
      "priority": "P2",
      "micro_intent": "patient_context"
    },
    {
      "query_id": "RZQ-01459",
      "question": "What if cost or availability makes losartan difficult to continue?",
      "priority": "P2",
      "micro_intent": "patient_context"
    },
    {
      "query_id": "RZQ-01460",
      "question": "My doctor mentioned losartan. What are the most important questions I should ask?",
      "priority": "P2",
      "micro_intent": "natural_language"
    },
    {
      "query_id": "RZQ-01461",
      "question": "I am already taking losartan. What should I track before my next review?",
      "priority": "P2",
      "micro_intent": "natural_language"
    },
    {
      "query_id": "RZQ-01462",
      "question": "How do I know whether my problem with losartan is the dose, the drug, or the treatment goal?",
      "priority": "P2",
      "micro_intent": "natural_language"
    },
    {
      "query_id": "RZQ-01463",
      "question": "What information would a clinician need to make a good decision about losartan?",
      "priority": "P2",
      "micro_intent": "decision_path"
    },
    {
      "query_id": "RZQ-01464",
      "question": "What is the shortest evidence-based decision summary for losartan?",
      "priority": "P2",
      "micro_intent": "summary"
    }
  ],
  "evidence": [
    {
      "label": "MedlinePlus drug information: Losartan",
      "url": "https://medlineplus.gov/druginfo/meds/a695008.html"
    },
    {
      "label": "DailyMed current human drug-label search: Losartan",
      "url": "https://dailymed.nlm.nih.gov/dailymed/search.cfm?labeltype=human&query=losartan"
    },
    {
      "label": "NHS medicine information: Losartan",
      "url": "https://www.nhs.uk/medicines/losartan/"
    }
  ],
  "review": {
    "visible_page_review_date": null,
    "object_generated_date": "2026-09-11",
    "claim_level_confidence": "not_assigned",
    "confidence_note": "This object preserves answer text and citations already present on the canonical page. Claim-level confidence scoring and source-provenance grading are deferred to the later evidence/provenance phase."
  },
  "safety": {
    "educational_only": true,
    "not_individual_prescribing_advice": true,
    "do_not_stop_or_change_prescription_without_clinician_review": true
  },
  "implementation": {
    "preferred_rendering": "answer-first blocks + machine-readable JSON",
    "new_url_required": false,
    "canonical_page_remains_primary": true
  }
}